RNA-based technologies are a powerful molecular biology toolbox, empowering scientists to decipher the complexities of living ...

Among the major classes of RNAs in the cell, tRNAs remain the most difficult to characterize via deep sequencing approaches, as tRNA structure and nucleotide modifications can each interfere with cDNA ...

How do mRNA vaccines work? mRNA vaccines teach the immune system to target specific proteins, often proteins found on a pathogen, like a virus. To do this, they use instructions carried in a ...

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In a report released today, Terence Flynn from Morgan Stanley maintained a Hold rating on Moderna (MRNA – Research Report), with a price target of $32.00. The company’s shares closed yesterday ...

Room-temperature stability aims to address significant supply chain challenges associated with some mRNA vaccines, including the dependence on ultra-low-temperature storage and complex delivery ...

The four nucleotides in mRNA form 64 unique codons, comprising 61 sense codons and 3 stop codons. Certain gene mutations can convert 18 of the 61 sense codons into stop codons. When this happens, the ...

Objective To estimate the effectiveness of messenger RNA (mRNA) booster doses during the period of Delta and Omicron variant dominance. Design We conducted a matched test-negative case–control study ...

This is known as a mixed vaccine series. The National Advisory Committee on Immunization (NACI) recommends an mRNA vaccine (Pfizer-BioNTech Comirnaty ® or Moderna Spikevax ®) should be offered for ...

Stop codons can sometimes be reinterpreted, allowing the cell to insert an amino acid rather than halting translation. This normally requires a specific signal in the mRNA that guides the ribosome ...

The United States led the world in developing the technology that beat the COVID-19 pandemic. Action from lawmakers may leave that legacy—and a $70 billion market—behind.