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Talazoparib and Enzalutamide Combination Improves Survival in Some Patients With Prostate Cancer
“The TALAPRO-2 study showed a significant improvement in overall survival in men with mCRPC treated with the combination of talazoparib and enzalutamide whether they had HRR gene alterations. In this ...
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Additional Noteworthy Studies to be Presented During 2025 ASCO Genitourinary Cancers Symposium
ALEXANDRIA, Va. – Nine studies exploring new approaches for the treatment of genitourinary cancers will be presented at the upcoming 2025 American Society of Clinical Oncology (ASCO) Genitourinary ...
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FDA Approves Brentuximab Vedotin with Lenalidomide and Rituximab for Relapsed or Refractory Large B-Cell Lymphoma
The following is a message from the Director of the FDA Oncology Center of Excellence, Dr. Richard Pazdur: On February 11, 2025, the Food and Drug Administration approved brentuximab vedotin (Adcetris ...
asco.org11d
Lisavanbulin in patients with recurrent glioblastoma: Phase 2a results and a consolidated analysis of response-predictive biomarkers.
Study phase and tumor characteristics of patients with GBM or G4 astrocytoma Number of patients treated with 15–30 mg/day lisavanbulin Number of patients with Objective response Best response and ...
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Phase 1 dose escalation study of MH048, a novel and non-covalent BTK inhibitor in patients with relapsed or refractory B-cell malignancies.
This material on this page is ©2025 American Society of Clinical Oncology, all rights reserved. Licensing available upon request. For more information, please ...
asco.org5d
Tumor mutational load, microsatellite instability and actionable mutations in metastatic colorectal cancer: Results from the TRIBE2 study.
Department of Translational Research and New Technologies in Medicine and Surgery, Unit of Medical Oncology 2, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy ...
asco.org5d
Phase II trial of neoadjuvant gemcitabine (G) and cisplatin (C) with sunitinib in patients (pts) with muscle-invasive bladder cancer (MIBC).
This material on this page is ©2025 American Society of Clinical Oncology, all rights reserved. Licensing available upon request. For more information, please ...
asco.org6d
A phase Ib trial of the VEGF fusion protein HB002.1T plus chemotherapy in patients with advanced solid tumors.
This material on this page is ©2025 American Society of Clinical Oncology, all rights reserved. Licensing available upon request. For more information, please ...
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Impact of adding nivolumab to first-line chemotherapy in patients with advanced gastric cancer.
This material on this page is ©2025 American Society of Clinical Oncology, all rights reserved. Licensing available upon request. For more information, please ...