Background Fibrolamellar carcinoma (FLC), a rare and fatal liver cancer lacking effective drug therapy, is driven by the DNAJ ...

Objective Symptoms in gastroparesis (Gp) and functional dyspepsia (FD) overlap; using egg protein substitute to measure gastric emptying of solids (GES), ~40% of patients are reclassified from Gp to ...

Correspondence to Professor Francis K L Chan, Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong, China; fklchan{at}cuhk.edu.hk Objective Patients with a history of Helicobacter ...

Introduction Maintenance of enteral nutrition is considered to be beneficial for patients in whom the oral access has been lost. For long term tube feeding, PEG (percutaneous endoscopic gastrostomy) ...

Introduction Osteoporosis is common in Crohn’s disease patients. 1 Autophagy genes have so far never being studied as potential risk factors for osteoporosis in Crohn›s disease. Methods We have ...

Introduction Patients with chronic liver disease have increased risk of bone disease (BD) with reported prevalence of osteoporosis (OP) between 12%–55% and a high prevalence of Vitamin D deficiency.

a Fibrosis Group, Clinical Sciences Unit, University of Queensland Department of Medicine and Queensland Institute of Medical Research, Brisbane, Australia, b Department of Pathology, Royal Brisbane ...

Correspondence to Professor Jingmei Jiang, Department of Epidemiology and Biostatistics, Chinese Academy of Medical Sciences and Peking Union Medical College Institute of Basic Medical Sciences, ...

Introduction Delivering better outcomes for cancer is a major part of the Long Term Plan for the NHS. For colo-rectal cancer (CRC) better outcomes will mainly come from earlier diagnosis of CRC and ...

Background: Mouse models of colitis and cancer are indispensable for our understanding of the pathogenesis of these diseases. In the past, mice had to be sacrificed in order to analyse colitis ...

Background There is no clinically relevant serological marker for the early detection of oesophageal adenocarcinoma (EAC) and its precursor lesion, Barrett’s oesophagus (BE). Objective To develop and ...

Introduction The National Institute for Health and Care Excellence (NICE) set standards for the management of chronic pancreatitis. This study aims to review the compliance with these guidelines of ...