2 Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China Introduction Metastatic disease of the hip causes severe pain and is a serious threat to the patient’s motor function.

Original research: A phase I, open-label, multicentre, first-in-human study to evaluate safety, pharmacokinetics and efficacy of AMG 404, a PD-1 inhibitor, in patients with advanced solid tumours (2 ...

Objective To assess the clinical and haemodynamic effects of carvedilol for patients with cirrhosis and portal hypertension. Design A systematic review and meta-analysis. Data sources We searched ...

Objectives The relationship between the volume of medical procedures conducted in hospitals and the resulting health outcomes has been described for various surgical and non-surgical medical ...

Objectives This study aimed to investigate the association between the type and severity of disabilities and depression among adolescents aged 15–17 years living in underdeveloped areas of Indonesia.

1 NIHR Greater Manchester Primary Care Patient Safety Translational Research Centre, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK 2 Manchester Centre for Health ...

Objectives To assess the completeness and representativeness of body mass index (BMI) data in the Clinical Practice Research Datalink (CPRD), and determine an optimal strategy for their use. Design ...

Objective Better knowledge of hepatitis B virus (HBV) infection prevalence at the national level can help to implement pertinent strategies to address HBV related burden. The aim was to estimate the ...

Objective Areca nut is one of the most widely consumed substances globally, after nicotine, ethanol and caffeine and classified as carcinogenic to humans. This study examines the disparity and ...

Objective Patients with chronic kidney disease (CKD) requiring kidney replacement therapy (KRT) in rural communities encounter many barriers in accessing equitable care and have worse outcomes ...

Introduction Interstitial lung disease (ILD) patients may develop a progressive phenotype usually characterised by ...

Objective Osteoporosis is a common disease in postmenopausal women. Several studies have analysed the associations between dietary supplementation with probiotics and bone health in postmenopausal ...