Research into splicing mechanisms and patterns is essential for decerning fundamental biological principles, as well as clarifying the molecular basis of many diseases and developing new therapies. 2 ...

An elegant screening strategy unveils a molecular actor that connects widespread changes in mRNA processing with a nutrient-sensing protein modification.

Cambridge, Massachusetts-based Envisagenics focuses on using AI to analyse errors in RNA splicing, a process in which a precursor form of messenger RNA (mRNA) – which is used as a template for ...

In higher eukaryotes, a vast variety of RNAs is transcribed from genomic DNAs. The transcribed RNAs are subjected to RNA processing steps, such as splicing, ...

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns ...

The interaction between RNA-binding proteins (RBPs) and circular RNAs (circRNAs) has emerged as a key area of interest in understanding cancer biology.

The ASO for myotonic dystrophy type 1 was well tolerated and improved splicing and function in a study presented at ASGCT.

The combined results of their research, including work in mouse models, indicated that the effects of TREs interfere with a critical process called gene splicing, which is essential for gene function.