Three main types of RNA are involved in protein synthesis: mRNA, tRNA, and rRNA. mRNA is synthesized by the enzyme RNA polymerase. This occurs by using the sequence of bases in a DNA strand to ...

When RNA molecules are synthesized by cells—a critical process in the creation of proteins and other cellular functions—they ...

RNA is generally single-stranded, as DNA is transcribed by RNA polymerases into mRNA (messenger RNA), which ... ribosomal and small nuclear RNA (tRNA, rRNA, snRNAs) fold into unique structures ...

This manuscript characterizes a mutated clone of RNA polymerase I in yeast, referred to as SuperPol, to understand the mechanisms of RNA polymerase I elongation and termination. The authors present ...

An elegant screening strategy unveils a molecular actor that connects widespread changes in mRNA processing with a nutrient-sensing protein modification.

They also found that in mRNA, early folding dictates the final folded shape, so molecular structure is set from the start. In rRNA, however, early shapes are temporary and rearrange before a molecule ...

In recent years, mRNA technology enabled the rapid development of vaccines to fight COVID-19, saving millions of lives. That same mRNA-powered approach to medicine—in which synthetic mRNA is ...

In recent years, mRNA technology enabled the rapid development of vaccines to fight COVID-19, saving millions of lives. That same mRNA-powered approach to medicine—in which synthetic mRNA is ...