Transfer ribonucleic acid (tRNA) is a type of RNA molecule that helps decode a messenger RNA (mRNA) sequence into a protein. tRNAs function at specific sites in the ribosome during translation ...

The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But where does translation take place within a cell?

US-based biotechnology company Alltrna is developing transfer RNA (tRNA)-based therapies that aim ... gene editing, or mRNA, ...

Tevard Biosciences, Inc., a privately held biotechnology company pioneering tRNA-based therapies to cure a broad range of ...

RNA breaks destined for repair are inflicted by sequence-specific or structure-specific endoribonucleases during physiological RNA processing (e.g. tRNA splicing; kinetoplast mRNA editing) and under ...

In particular, we are working to answer questions that include: (1) How does the cell read, write, and erase diverse chemical modifications on mRNA and tRNA to impact RNA structure, translation, and ...

Each tRNA molecule has an anticodon that is complementary to a specific codon on the mRNA. The tRNA binds to its corresponding amino acid and transports it to the ribosome, where it is incorporated ...

Messenger RNA (mRNA) carries the genetic information from DNA to the ribosomes, where proteins are synthesized. Transfer RNA (tRNA) and ribosomal RNA (rRNA) are involved in the translation of mRNA ...

First described in the 1960s, tRNA molecules are cross-shaped nucleotide loops that attach to an amino acid on one arm and recognize a specific mRNA codon with another. Canonically, their sole purpose ...

Among the major classes of RNAs in the cell, tRNAs remain the most difficult to characterize via deep sequencing approaches, as tRNA structure and nucleotide modifications can each interfere with cDNA ...