The yeast RGG motif-containing RNA binding protein Scd6 and its human ortholog LSM14A regulate the translation of specific ...

Single-cell RNA sequencing (scRNA-seq) has confirmed that MM exhibits high intra-tumor heterogeneity, comprising a mixture of ...

Explore the impact of 3D models in drug discovery and how they enhance predictive insights in pre-clinical research.

The identification and intervention of Alzheimer's Disease (AD) in its early-stage allows for the timely implementation of lifestyle modifications and therapeutic strategies. Although dysregulation of ...

Researchers from Agency for Science, Technology and Research in Singapore recently published a review article exploring how chromatography can be used to remove double-stranded RNA impurities during ...

Lung cancer (LC) is a major global health issue, with high mortality rates and limited therapeutic options. It is primarily categorized into non-small cell lung cancer (NSCLC) and small cell lung ...

A review paper published last year in European Journal of Medicinal Chemistry characterized Myc as the “oncogene from ...

Stop codons can sometimes be reinterpreted, allowing the cell to insert an amino acid rather than halting translation. This normally requires a specific signal in the mRNA that guides the ribosome ...

Lung cancer (LC) is a major global health issue, with high mortality rates and limited therapeutic options. It is primarily categorized into non-small ...

Follow-up studies confirmed that this nucleoside modification improved mRNA translation capabilities and stability. In the last decade, a series of studies highlighted the powerful potential of ...