The yeast RGG motif-containing RNA binding protein Scd6 and its human ortholog LSM14A regulate the translation of specific ...

The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But where does translation take place within a cell?

Single-cell RNA sequencing (scRNA-seq) has confirmed that MM exhibits high intra-tumor heterogeneity, comprising a mixture of ...

An in-depth analysis of this transferred mRNA revealed that mRNAs coding for molecules related to transcription, translation, ...

Bin Wu, associate professor in the department of Biophysics and Biophysical Chemistry at the School of Medicine, visited ...

Follow-up studies confirmed that this nucleoside modification improved mRNA translation capabilities and stability. In the last decade, a series of studies highlighted the powerful potential of ...

The identification and intervention of Alzheimer's Disease (AD) in its early-stage allows for the timely implementation of lifestyle modifications and therapeutic strategies. Although dysregulation of ...

Regulation of the poly(A) tail is essential for selective protein translation in early embryos. However, the mechanisms that determine and maintain the length of maternal mRNA poly(A) tails remain ...

View Full Profile. Learn about our Editorial Policies. 3’ UTRs encode information about mRNA localization, translation efficiency, and stability (1). 1 mRNA is packaged with translational machinery ...

By quantifying the number of mRNA transcripts, the ones inside the cell and those bound to ribosomes, the team found that the translation efficiency of the branched mRNA was approximately 1.5 times ...

Get Instant Summarized Text (Gist) A novel class of zwitterionic phospholipids, specifically DOPE-Cx, significantly enhances mRNA delivery by facilitating endosomal escape, a major challenge in ...