Heidelberg biochemists and structural biologists from Shanghai unravel the roles of two key regulatory factors in mRNA splicing. Two molecular control factors play a key role in splicing, the process ...

Fred Hutch and MSK researchers showed that tumors driven by hiccups in RNA processing can't hid from the immune system. In ...

A team of scientists led by the A*STAR Genome Institute of Singapore (A*STAR GIS) have released one of the world's largest ...

Researchers suggest discovery of genetic link between ASD and DM1 opens up potential new therapeutic avenues for ASD.

In recent years, mRNA technology enabled the rapid development of vaccines to fight COVID-19, saving millions of lives. That same mRNA-powered approach to medicine—in which synthetic mRNA is ...

RNA splicing is a modification of the nascent pre-messenger RNA (pre-mRNA) transcript in which introns are removed and exons are joined prior to translation. For many eukaryotic introns ...

However, mRNA itself is an exceptionally unstable molecule. This does not affect the safety of the therapy but limits its effectiveness—for example, by shortening the duration of action.

Messenger Ribonucleic Acid (mRNA) vaccines gained global recognition during the Coronavirus Disease 2019 (COVID-19) pandemic, proving their value through rapid development, high efficacy ...

The world was desperate for scientific solutions. PREMIUM Vials of Covid-19 mRNA vaccines. (Reuters File Photo) I remember vividly the wave of hope that arrived in November 2020 when Pfizer ...

They found that mRNA-based COVID-19-vaccinations cause a significant and persistent change through acetylation, i.e., the binding of a chemical group to specific, immunologically relevant genes of ...

The mRNA Cancer Vaccines and Therapeutics Market has emerged as one of the most promising sectors within the biotechnology and oncology landscape. mRNA, or messenger RNA, serves as a genetic blueprint ...