Therapies involving mRNA, a key to Covid vaccines, hold great potential in treating several diseases, but some lawmakers want ...

Vaccines using mRNA are currently being studied for a wide range of diseases, including cancer, cardiovascular disease, ...

The discovery of the Kozak consensus sequence revealed that certain nucleotide contexts around the initiation codon can significantly enhance the efficiency of initiation codon recognition. Since then ...

An 11-year-old from Rowlett is set to make medical history as the first person in the world to receive treatment for NARS1.

When RNA molecules are synthesized by cells—a critical process in the creation of proteins and other cellular functions—they ...

For example, during SARS-CoV-2 infection, both T and B lymphocytes play critical roles in viral clearance and the generation ...

The FDA has granted rare paediatric disease and orphan drug designations for IN013, Innorna's mRNA therapeutic for Wilson's ...

Among the major classes of RNAs in the cell, tRNAs remain the most difficult to characterize via deep sequencing approaches, as tRNA structure and nucleotide modifications can each interfere with cDNA ...

Division of Pharmacoengineering and Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States ...

We found that arginine limitation in pancreatic tumors perturbs saturated and monounsaturated fatty acid synthesis by suppressing the lipogenic transcription factor SREBP1. Synthesis of these fatty ...