Replacing PEG with PCB in lipid nanoparticles led to potent mRNA vaccines that avoided unwanted immune responses.

A new material developed at Cornell University could significantly improve the delivery and effectiveness of mRNA vaccines by ...

This is therefore an opportune time to check in and provide an update on the mRNA/LNP litigation landscape. Recall the Comirnaty® and Spikevax® mRNA-based vaccines each utilize lipid nanoparticles.

LNP development has been a headache, but without this packaging, mRNA vaccines would be nothing. “It is the unsung hero of the whole thing,” says Giuseppe Ciaramella, who was head of ...

Lipid nanoparticle (LNP) mRNA vaccines emerged during the COVID-19 pandemic to form an almost miraculous protection against a virus, which killed millions around the world. Aided by expedited ...

Population-adjusted indirect comparison (PAIC) of avelumab (AVE) and retifanlimab (RETI) in the first-line (1L) treatment of patients (pts) with metastatic Merkel cell carcinoma (mMCC). Survival ...