Professor Hirohide Saito (Department of Life Science Frontiers at CiRA / The University of Tokyo) and Assistant Professor ...

This unique property facilitates membrane fusion-mediated endosomal escape, leading to improved mRNA expression in the liver compared to conventional phospholipids such as DSPC and DOPE. "Endosomal ...

Investigating how mutations in tumors alter DNA’s 3D structure—and subsequently, regulatory sequences called enhancers—can ...

Summary: New research reveals how a tiny chemical mark on RNA helps wire the brain during development. Scientists discovered ...

Gene expression is dynamic, ... Both Northern blots and SAGE analyses work by measuring levels of mRNA, the intermediary between DNA and protein. Remember, in order to activate a gene, ...

A significant correlation was found between faecal COX-2 mRNA expression and faecal B2M, CEA, E-cad, or CD45 mRNAs, markers of exfoliated total cells, colonocytes, and leukocytes, respectively.

When they viewed the expression patterns for the isolated mRNA, to their surprise they observed that some genes in dopamine neurons showed abundant expression of 3′ UTR mRNA sequences and little ...

The mRNA is expressed in target cells for clinical translation and purified by high-performance liquid chromatography to remove double-stranded RNA contaminants and increase protein expression in ...

Additionally, mRNA expression lasted up to four weeks -- significantly longer than the typical five-day expression period of LNPs. Notably, ...

Researchers examined the vaccination effects and local antigen expression efficiency of a needle-free vaccination technique involving pyro-drive liquid jet injection (PYRO) to deliver the naked ...