mRNA is incredibly delicate ... The team made about 100 ionizable lipids and introduced ester linkages into the carbon chains of the lipids to help make them more biodegradable, he recalls.

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During this process, the ribosomes link together amino acids into chains resulting in the production of a new protein. With the help of the SKI complex, mRNA is transported to the exosome if it is ...

Dr Wiklund added that mRNA vaccines require cold chain storage, so aren’t ideal for use in more difficult locations. He explained: “For more permanent pathogens, for example, polio or measles ...