Epigenetic reprogramming holds promise for reversing aging, addressing cellular aging mechanisms and paving the way for innovative therapeutic strategies.

Single-cell RNA sequencing (scRNA-seq) has confirmed that MM exhibits high intra-tumor heterogeneity, comprising a mixture of ...

Researchers from Agency for Science, Technology and Research in Singapore recently published a review article exploring how ...

Located unusually early in the protein sequence, the stop codon would be expected to end the transcription ... halting translation. This normally requires a specific signal in the mRNA that ...

Bin Wu, associate professor in the department of Biophysics and Biophysical Chemistry at the School of Medicine, visited ...

A review paper published last year in European Journal of Medicinal Chemistry characterized Myc as the “oncogene from ...

Lung cancer (LC) is a major global health issue, with high mortality rates and limited therapeutic options. It is primarily categorized into non-small ...

Follow-up studies confirmed that this nucleoside modification improved mRNA translation capabilities ... can be used to quantify mRNA via reverse transcription and PCR amplification.

One study outlined the key areas that need to be overcome: the stability, immunogenicity, translation ... “Larger mRNA-based therapeutics are synthesised by in vitro transcription, which is ...