The immunosuppressant drug tacrolimus may significantly improve relapse-free survival vs. mycophenolate mofetil for children with frequently relapsing nephrotic syndrome, according to study data.

Based on their experience, Lee's team recommended holding tacrolimus during the 5-day course of nirmatrelvir/ritonavir (or even 1 to 2 days prior to starting the antiviral for high-risk patients ...

[20,22,25] Lower tacrolimus disposition in young children might be related to an increased tacrolimus intestinal first pass metabolism resulting from higher CYP3A4 and CYP3A5 expression in the ...

Tacrolimus and cyclosporine A show similar efficacy in long-term survival and relapse reduction in AML post-transplant patients. No significant differences were found in leukemia-free survival ...

This paper reviews the currently available evidence on the use of topical tacrolimus in atopic dermatitis and other conditions, as well as its safety profile and cost-effectiveness.

Tacrolimus is available in the form of a capsule, granules for oral suspension (to be mixed with liquid), an extended-release capsule and a tablet to be taken orally.

To achieve recommended concentrations of tacrolimus in the body, clinicians often prescribe to Black kidney transplant patients higher doses of the drug than white recipients, she explains. Despite ...

The immunosuppressive agent tacrolimus, commonly used for solid organ transplantation, may have a therapeutic role in systemic lupus erythematosus (SLE), particularly for lupus nephritis, European ...