We created novel artificial cells by encapsulating a riboswitch-gene fusion with wheat germ extract in liposomes. These non-living cells promoted the expression of a glowing protein encoded in the ...

The riboswitch technology is just part of MeiraGTx’s work in gene therapy. The company has technologies for the optimization of adeno-associated virus (AAV) vectors and for the design of ...

The riboswitch is specific enough that it doesn't bind caffeine, which is structurally similar to theophylline. The bacteria migrate as a function of theophylline concentration, heading toward ...

Riboswitches are widely distributed, conserved RNAs which regulate metabolite levels in bacterial cells through direct, noncovalent binding of their cognate metabolite. Various riboswitch families are ...

MeiraGTx to receive $50 million milestone after initiation of the extension study for the Phase 3 LUMEOS clinical trial for botaretigene sparoparvovec (bota-vec, formerly AAV-RPGR) for the ...

Sanofi is making a $30 million investment in MeiraGTx to gain a first peek at data from the biotech’s riboswitch platform to brew up some new deals.

Sanofi to purchase $30 million of ordinary shares of the Company at a price of $7.50 per share Sanofi to receive a right of first negotiation for the use of MeiraGTx’ s Riboswitch gene ...

When the preQ 1 molecule binds, the riboswitch twists to communicate to the RNAP to continue transcription. These observations were further rationalized and validated through a collaborative effort ...

To prevent a global health crisis, scientists around the world are searching for ways to fight bacteria that can evade the current arsenal of antibiotics.

To prevent a global health crisis, scientists around the world are searching for ways to fight bacteria that can evade the current arsenal of antibiotics.

The riboswitch was designed to regulate the expression of human erythropoietin (hEPO). This protein is used to treat anemia associated with chronic kidney disease and is an attractive target for ...

Turning genes on and off as easily and predictably as flicking a switch could be a powerful tool in medicine and biotech. A type of technology called a riboswitch might be the key.