Using Argonaute high-throughput sequencing of RNAs isolated by cross-linking immunoprecipitation analysis ... Center for Membrane and Structural Biology and ‡Center for RNA Molecular Biology, Case ...

This revolution is being powered by RNA technology — and Canada is uniquely positioned to lead it. While the swift development of COVID-19 vaccines appeared to be a sudden scientific triumph ...

Stanford Medicine researchers have developed a blood test capable of detecting cancers, the ways cancer resists treatments and tissue injury caused by non-cancerous conditions. The new test ...

Get Instant Summarized Text (Gist) A long-read RNA sequencing dataset comprising 750 million reads across 14 human cell lines enables direct observation of full-length RNA molecules, overcoming ...

How do mRNA vaccines work? mRNA vaccines teach the immune system to target specific proteins, often proteins found on a pathogen, like a virus. To do this, they use instructions carried in a ...

We subsequently evaluated the binding affinity of LARP7 mutants to 7SK snRNA by using RNA immunoprecipitation (RIP)-qPCR. The results showed that the 49KA mutant almost completely lost the binding of ...

The researchers tested the RNA origami in a lipid vesicle, a simple cell model system widely used in biology. Using so-called RNA aptamers, the artificial cytoskeleton was bound to the cell membranes.

Abstract: RNA-binding proteins (RBPs) are the master regulators of mRNA processing, which are vital players for the post-transcriptional control of gene expression. In recent years, crosslinking ...

Daiichi Sankyo is stepping up its interest in RNA therapies, teaming with Nosis Biosciences to design drug candidates capable of reaching targets beyond the liver. The Japanese drugmaker is best ...

Unpaired two-tailed t test was performed to compare means of samples against controls. A) Western blot of DNA:RNA hybrid immunoprecipitation (DRIP) from adult mouse retina showing immunoblot (IB) ...

Get Instant Summarized Text (Gist) RNA sequencing has been clinically validated for whole-transcriptome analysis, enhancing genetic diagnostics for Mendelian diseases. This test, developed at ...