The systemic delivery of drugs via the inhaled route is an attractive, needle-free means of improving the systemic exposure of molecules such as peptides and proteins that are poorly absorbed after ...

Glucan-mediated trained immunity activates alveolar macrophages which exacerbates acute lung injury induced by LPS.

Bovine lung, with acute pulmonary edema and emphysema with proliferation of type II pneumocytes and formation of hyaline membranes strongly adhered to the alveolar wall.

An analysis of experimental data on the pulmonary alveolar sheet of the cat shows: (1) As far as elasticity in the plane of the sheet is concerned, the alveolar sheet may be regarded as uniform; the ...

Within the prior 24 months, I have had a financial relationship with a company producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients: Receive the the ...

Neurogenic pulmonary edema, however, has been assumed to be secondary to elevated left atrial and left ventricular end-diastolic pressures. If a specific relation exists in these patients, the ...

2 Studies on the role of metabolic abnormalities in alveolar epithelial cells during pulmonary fibrosis The lung is a metabolically active organ that plays an important role, though its importance is ...

Idiopathic pulmonary fibrosis (IPF) remains an age-related, fatal, incurable, epithelial-driven fibrotic lung disease despite the availability of approved antifibrotic drugs. The medical need for ...

Here, we report that myeloid RACK1 deficiency results in the scarcity of mature AMs and pulmonary alveolar proteinosis. A mixed bone marrow chimera approach reveals a cell-intrinsic role of RACK1 in ...