This important study presents compelling observational data supporting a role for transcription and polysome accumulation in the separation of newly replicated bacterial chromosomes. The study is ...

Polysome-qPCR can quantify the polysome distribution and translation rate of IRES-containing mRNA isoforms in an isoform-sensitive manner from embryonic tissues. A key reason for our poor ...

Antonia was not always a scientist, beginning her higher education with a joint science and arts degree at the University of Guelph in 2015. After exploring her interests in a range of non ...

KCL Department of Biophysics: glass and acetate slides ('quarter plates', 'whole plates' and 'half plates') relating to the work of the Medical Research Council (MRC) Biophysics Research Unit (KCL ...

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Writing in Science Advances researchers of the University of Cologne describe a key mechanism that controls the decision-making process that allows human embryonic stem cells to make the heart.

Decision letter after peer review: Thank you for submitting your article "Polysome-CAGE of TCL1-driven chronic lymphocytic leukemia revealed multiple N-terminally altered epigenetic regulators and a ...

Polysomal profiling has emerged as a tool to identify mRNAs that are actively translated. The association of the mRNA to the polysome, also referred to as translatome, provides a proxy for mRNA ...

Polysome profiling, the first translatomics technique, has been valuable in translational studies – uncovering dynamics of ribosome occupancy and density. Ribosome profiling is another promising ...

We found that K63 ubiquitinated ribosomes are also present in a polysome arrangement, similar to that observed in yeast polysomes, which we determined using cryoelectron tomography (cryo-ET). We ...