KT-621 (STAT6) Phase 1 healthy volunteer trial ongoing, complete SAD/MAD data expected in June 2025 KT-621 Phase 1b trial in atopic dermatitis (AD) patients expected to initiate in 2Q25 with data in ...

The Price to Earnings (P/E) ratio, a key valuation measure, is calculated by dividing the stock's most recent closing price by the sum of the diluted earnings per share from continuing operations ...

Anterior gradient 2 (AGR2) is a protein located in the endoplasmic reticulum involved in protein folding and when stressed, it is secreted into the extracellular space and it attracts monocytes, ...

Signal transducer and activator of transcription 6 (STAT6) is a member of the STAT family involved in the regulation of immune response and inflammation. The development of SH2 domain inhibitors ...

Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...

Last week, Gilead Sciences, Inc. GILD reported better-than-expected fourth-quarter results. Adjusted earnings per share (EPS) of $1.90 beat the Zacks Consensus Estimate of $1.67. In the year-ago ...

Activation of an immune signaling molecule called STAT6 may lead to pulmonary hypertension (PH) in people with oxygen deprivation due to obstructive sleep apnea, according to a recent study in mice.

Solitary Fibrous Tumors (SFTs) are a rare malignancy defined by NAB2-STAT6 fusions. Because the molecular understanding of the disease is largely lacking, there are currently no targeted treatment ...

The longer NAB2-STAT6 is expressed the more cells (Dox) move further along the PC1 axis (27% of variance), suggesting NAB2-STAT6 induces broad and consistent transcriptome changes in U2OS cells. (b) ...

To highlight the limitations of UMAP above, we apply PCA: The first principal component (PC1) separates West African and European populations. This clear separation aligns with well-understood genetic ...

PC2 is a Contest Control System for ICPC-style programming contests. It is free and is among the most widely-used contest control systems in the world.

NOTE: The gain function will not work for audio sources coming from the computers (PC1, PC2, PROD_PC). You must amplify the audio by raising the volume on the playback program, and/or the computer ...