The NFL officially released its full slate of games for the 2025 season on Wednesday. The schedule is full of intrigue as the Bills look to build toward their sixth-consecutive AFC East crown. However, Buffalo will face off against multiple teams that have ended their season in recent years.

The NFL schedule is finally out, and the Buffalo Bills have the fifth easiest schedule, but that doesn't mean there aren't teams that can trip them up in 2025.

As two of the most dynamic quarterbacks in the NFL, Allen and Jackson's careers have been connected in multiple facets. The two engaged in a razor-thin 2025 MVP race that Allen narrowly edged. However, Jackson claimed the 2024 MVP, making the Week 1 matchup a face-off between the two most recent award winners.

In Week 14 of the 2025-26 season, Joe Burrow and the Bengals will face Josh Allen and the Bills for the fourth time (if you count the cancelled game). And there are sure to be offensive fireworks between two of the top three quarterbacks in the game.

NFL schedule was released on Wednesday night, and there is plenty to talk about when it comes to this upcoming season. The Dallas Cowboys and Philadelphia Eagles will kick off things on Sept. 4, followed by the Los Angeles Chargers and Kansas City Chiefs in Sao Paulo,