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This pathway, or others like it, could explain why some inheritable traits between generations can’t be explained exclusively via DNA and RNA. "There are a lot of traits and disorders that we ...

Such growth alteration is commonly caused by pathogenic variants in genes associated with the regulation of longitudinal growth. Your height may hinge on an obscure DNA repair protein – Variants ...

Biosensors and Nanobiotechnology Laboratory, Integrated Science Building, Faculty of Science, Universiti Brunei Darussalam, Jalan Tungku Link, Gadong BE1410, Brunei Darussalam ...

According to a study by the Manchester Fungal Infection Group, in 2022, approximately 6.5 million people were infected by a pathogenic fungus ... Ribonucleic acid (RNA) plays a central role in the ...

School of Chemistry and Chemical Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, China ...

Type I Interferonopathy-associated variants of ARF1 disrupt retrograde transport of STING. Application of STING inhibitors reduce auto-inflammation of patient cells in vitro. ARF1 variants R99C and ...

In Mavs-knockout mice, Chen noted that cells were “totally defective in immune defense against RNA viruses ... its place as the elusive cytosolic DNA sensor to complete the cGAS-cGAMP-STING pathway.

Sensing of foreign DNA in the cytosol by the ... ssDNA and activation of the cGAS-STING-TBK1 pathway which conveys a survival advantage in the cancer cells. Pharmacological inhibition or depletion of ...