Understanding the immune system is fundamental to advancing biomedical research, especially in areas such as cancer, autoimmune diseases, and infectious diseases. Mouse models play a pivotal role in ...

Multiple assays and large volumes of patient serum are required for multivalent vaccines, so it is better to use a multiplexing approach; for example, a Luminex instrument to detect and quantify ...

Researchers have identified key immunological markers associated with mortality in hospitalised people living with HIV/AIDS.

Common applications include profiling cytokine concentrations in serum ... they read a microsphere-based assays.” The Luminex method uses microsphere sets carrying variable quantities of two ...

and further studied the expression of related cytokines receptors in IIMs. Methods: The Human 48-Plex Luminex assay for cytokines was performed in the serum of IIMs, including 93 untreated and 18 ...

The levels of inflammatory plaque cytokines (MCP-1, IL-8, IFN-γ, IL-10, IL-1β, IL-6, PDGF-AA, PDGF-AB/BB, TNF-α, VEGF) were measured in tissue homogenates using a customized 10-plex Luminex assay.

Multiple human cytokines in serum were simultaneously analyzed using a bead-based multiplex cytokine assay (Luminex, USA). Levels of IL-1β, IL-4, IL-6, C-C motif chemokine ligand 2 (CCL2), interferon ...

This study presents valuable findings by using Fmr1 knockout mice as a model to investigate the role of Fmr1 in sleep regulation. These mice exhibited clear evidence of sleep and circadian ...

19 MMP and cytokine concentrations in BAL were quantitated using a microparticle-based multiplex immunoassay (R&D systems, Abingdon, UK) developed by Luminex. Samples were ... (see online ...

Design Longitudinal muscle and myenteric plexus from small intestine of young, mid-aged and old mice were dissected and prepared for whole mount immunostaining, flow cytometry, Luminex immunoassays ..