Large cell neuroendocrine carcinoma (LCNEC), a rare and aggressive type of lung cancer, has a high chance of metastasis, no standard treatment and a poor survival rate. A study published in Nature ...

Using molecular docking and molecular dynamics (MD) simulations, we analyzed the binding mechanisms, key interacting residues, and the dynamics of the CD147-SP complex with heparin. These insights not ...

The Hsieh-Wilson group also reported the synthesis of glycopolymers via ROMP, in their case of norbornene functionalized tetrasulfated disaccharide of l -iduronic acid and glucosamine to target the ...