the precious mRNA payload is encapsulated in lipid nanoparticles. Recent elegant cryogenic-transmission electron microscopy [Biophys J 120, 2766 (2021)] reveals that these lipid nanoparticles take the ...

P enn Engineers have cooked up a new way to improve mRNA delivery, developing an optimal "recipe" for ionizable lipids—key ingredients in lipid nanoparticles (LNPs), the molecules behind the ...

This new lipid nanoparticle production system developed by Shin-Etsu Chemical and Hokkaido University is capable of small-batch and mass production ...

Advancements in mRNA vaccine technology are reshaping medicine, addressing challenges and expanding applications from ...

Engineered functionalized phospholipids hold great promise for developing lipid nanoparticles (LNPs) used in mRNA vaccines, cancer treatment, protein replacement therapy, and more. The derivative ...

A key challenge remains finding a delivery system that enables enough of the mRNA to reach target tissues safely without causing adverse effects. Lipid nanoparticles have been studied since the ...

(Reuters File Photo) The research team from the University of Pennsylvania’s Perelman School of Medicine demonstrated that combining mRNA with a specialised lipid nanoparticle could reach areas ...

The global lipid nanoparticles market, valued at US$ 820.51 million in 2023, is projected to experience significant growth, with an expected market valuation of US$ 2,387.98 million by 2032. This ...

Phospholipids are key components of cell membranes, and are used in the creation of lipid nanoparticles (LNPs) for targeted drug delivery. DOPE-Cx can form a special structure called a “cubic phase,” ...

As we previously discussed, beginning in 2022, a series of patent infringement lawsuits were filed against Moderna and collaborators ...