Replacing PEG with PCB in lipid nanoparticles led to potent mRNA vaccines that avoided unwanted immune responses.

LNP development has been a headache ... the immune system has more time to spot the particles and start mounting an antibody response. And although PEG is found in many cosmetic, drug, and ...

OSE Immunotherapeutics. OSE Immunotherapeutics Announces Strategic Collaboration to Pioneer Novel mRNA Technologies. OSE ...

A new PEARLS article in PLoS Pathogens reviews the rapid evolution and pandemic potential of emerging influenza A viruses, ...

Acuitas evaluated an “active” targeting approach to LNP delivery using Athebody® designed ankyrin repeat proteins (DARPins) — antibody mimetic proteins that act as high-affinity and high-specificity ...

Innovative delivery techniques, including high-tech nanoparticles and electroporationdevices, may convey more gene therapies into the clinic.

In contrast, polyethylene glycol (PEG)-lipid standards, commonly used in current LNP formulations, elicited a strong and boosted antibody response. Anti-PEG antibodies have been implicated as a ...

In contrast, polyethylene glycol (PEG)-lipid standards, commonly used in current LNP formulations, elicited a strong and boosted antibody response. Anti-PEG antibodies have been implicated as a ...

The vaccine uses a lipid nanoparticle (LNP) delivery system to efficiently deliver neoantigen ... Preclinical data also demonstrated that the combination of EVM16 and a PD-1 antibody has synergistic ...

GERMANTOWN, MARYLAND / ACCESS Newswire / March 4, 2025 / uBriGene Biosciences (uBriGene), a leading cell and gene therapy CDMO, is pleased to announce the submission of its Drug Master File (DMF) for ...