In the first step, the 2'-OH of an adenosine in the intron (the branch site A) attacks the phosphodiester bond at the 5' splice site to release the upstream exon and form a branched or lariat ...

ProbeLibrary, a fast, specific and flexible format for quantitative real-time PCR, is described. The ProbeLibrary concept is based on the fact that just 90 short probes provide transcriptome-wide ...

This spliceosome is made up of variety of protein and RNA components, and for each splicing process, it is reassembled at the sites where an exon joins an intron and the intron in turn connects to ...