A 69-year-old St. Charles man was pronounced dead at the scene. Two other people were transported by ambulance in serious ...

The Missouri State Highway Patrol closed northbound Interstate 270 Tuesday afternoon for a fatal crash investigation. FOX 2's Caroline Pettey shares more.

A crash has closed lanes of northbound Interstate 270 in St. Louis County. Creve Coeur police said the northbound lanes of the interstate were closed at Highway 40 as of 2:15 p.m. on Tuesday. Two ...

A fatal crash on Interstate 270 has shut down several lanes this afternoon, causing significant traffic disruptions.

The Bellefontaine Conservation Area, located at Interstate 270 and Lewis and Clark Boulevard, will be part of a first-ever ...

Police said a couple followed the driver from near Interstates 64 and 270 in St. Louis County to Hazelwood and fired multiple ...

A couple followed a driver for nearly 14 miles through St. Louis County, then confronted him in a parking lot over a traffic dispute before firing shots at his vehicle, police say.

The crash happened on eastbound I-70 approaching the I-670 interchange, and as of 7:45 a.m. eastbound lanes were closed and traffic was being diverted onto Interstate 270, the dispatcher said.