This valuable work presents how PRDM16 plays a critical role during colloid plexus development, through regulating BMP signaling. Solid evidence supports the context-dependent gene regulatory ...

Researchers from Astrazeneca plc and Karolinska Institutet have described the positron emission tomography (PET) evaluation of [11C]AZD-2423, a chemokine receptor type 2 (CCR2) radioligand in ...

Joint injury induces rapid and sustained diversification of resident and infiltrating synovial macrophage phenotypes, underpinning osteoarthritis-associated synovitis.

Merge images show colocalization of oxPL in macrophage containing loci ... These studies provide proof of concept for targeted imaging of inflammation in atherosclerosis using a stable liposomal ...

An important implication of our studies is the ready translatability of these results to the imaging of macrophages in atherosclerosis and cancer. † All formulations contained 15 mol.% ...

A virtual reality system to image the brain in vivo Among the cutting-edge technologies the ISTA scientists used was a custom ...

Integrating live in vivo imaging with molecular genetic analyses, we demonstrate how rapid molecular adaptation upon environmental confinement (including fine-tuning of the nuclear lamina) primes ...

“In the future, advancements in real-time imaging of depth and the enhanced tracking ability of microplastic particles in vivo may further drive innovation in this area of study,” he says.

Design Flow cytometry, immunohistochemistry, confocal imaging and gene expression ... cells were determined in vitro and in vivo using APAP-treated WT mice. Conclusions We identify a hepatoprotective, ...

Fluorescent imaging was performed using ... Additionally, investigating different macrophage subtypes may reveal diverse interactions and roles in fibrosis progression. Since our model replicates lung ...