A groundbreaking antibiotic discovery might finally tip the balance in the global fight against drug-resistant bacteria.

A suspected member of the notorious Tren de Aragua (TdA) gang was among five people arrested during a human smuggling bust in Texas, authorities said Wednesday. The three suspects accused of human ...

Wright says this lack of toxicity to human cells is because human ribosomes are just different enough from bacterial ribosomes that lariocidin can’t bind to them. The team then infected mice with A.

Most of these antibiotics are produced outside the ribosome, the cellular structure ... resistance and has no cytotoxic effects on human cells. Its antimicrobial activity was even stronger in ...

triggers the deadenylation-dependent decay of inefficiently translated mRNAs in human cells. DDX6 interacts with the ribosome through the Phe-Asp-Phe (FDF) motif in its RecA2 domain. Furthermore, ...

Weber et al. investigated the role of human DDX6 in messenger RNA decay using CRISPR/Cas9 mediated knockout (KO) HEK293T cells. The authors showed that stretches of rare codons or codons known to ...

Ribosome collisions activate ZAK ... To conduct their research, the scientists exposed human cellular models to a UV lamp mimicking the sun's radiation. Using proteomics to understand cell ...

Together, the findings indicate that stress-induced ribosome dysregulation underlies human depression in a complex fashion. According to the authors, dysregulation of ribosomes may change the ...

This research has revealed that the ribosomes in bacteria operate very differently from those found in human cells; bacterial ribosomes are much faster than those in humans, but the ribosomes in human ...

Scientists at St. Jude Children’s Research Hospital revealed that human ribosomes decode messenger RNA (mRNA) 10 times slower than bacterial ribosomes, but do so more accurately. The study, published ...

Scientists have found that human ribosomes decode mRNA slower than bacteria, with implications for drug development. Scientists at St. Jude Children's Research Hospital revealed that human ...

These findings, published in Cell Reports, could lead to new ways to manipulate ribosome production, which could impact a variety of conditions that affect human health. "Ribosomes are fundamental ...