This transdisciplinary course will examine the interface between pathogens and their hosts a multiple levels. We will begin with molecular and cellular interactions between host and pathogen species ...
Infectious disease dynamics, including severity, spread, and patient outcome, are shaped by host-pathogen interactions at multiple scales (ex: molecular, cellular, organismal, ecological).
We will also establish how interaction with host immunity and exposure to drugs will drive the evolution of pathogens. Using our established track record in pre-clinical and experimental medicine ...
Simplistically, 'pathogenesis of infection' defines the way that a given pathogen influences a host's immune system. But how one understands the interaction between pathogen and host can differ ...
Pathogens must interact with host molecules, namely host proteins, to infect a host, evade the immune system, and cause ...
Active host-pathogen interactions take place during infection of human immunodeficiency virus type 1 (HIV-1). Outcomes of these interactions determine the efficiency of viral infection and ...
Nonetheless, much of disease ecology has historically focused on interactions between a single host and parasite species, despite growing evidence that changes in host and pathogen community structure ...
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Heterogeneous host populations drive evolution of more virulent pathogens, modeling study showsClassical evolutionary theory states that virulence evolves to maximize a pathogen's basic reproduction ratio, i.e., the average number of secondary infections caused by one infected host.
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