The beads are called nucleosomes. Each nucleosome is made of DNA wrapped around eight histone proteins that function like a spool and are called a histone octamer. Each histone octamer is composed ...

Specifically, PRC2 adds a well-known repressive tag called H3K27me3 to histone proteins; while PRC1 adds related tags, H2Aub or H2A.Zub, to the histone H2A or a variant histone called H2A.Z, ...

This enzyme is able to silence specific DNA sections by epigenetically modifying histone proteins that package the DNA. These modifications ensure that the DNA is densely packed as heterochromatin ...

Now, Warnecke and colleagues are challenging the idea that these space-saving proteins are not commonplace in bacteria. In a preprint uploaded to bioRxiv this January that has yet to undergo peer ...

A key enzyme and its molecular pathway are critical to keeping activated CD8+ T cells active and away from “exhaustion”, ...

modification and mutation locations are indicated by boxes and lines. For clarity, connections are only shown to a single copy of each histone protein.

The immune system can work in two ways: the innate immune system reacts to any foreign invaders that are identified by immune cells that look... | Cell And Molecular Biology ...

These attendant proteins bind to histones and nucleosomal DNA, and their binding to these molecules is affected by the histone modification state. The modification state helps determine whether ...

Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact on cellular function and human disease.

The BCG vaccine protects against tuberculosis, but by inducing trained immunity it also protects against many more ...

11 “The idea is that you chemically fix the cells to freeze everything in place, you dice the DNA all up into pieces, and then you take an antibody for [histone 3 lysine 27 trimethylation] or some ...