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More information: Yushin Ando et al, A mini-hairpin shaped nascent peptide blocks translation termination by a distinct mechanism, Nature Communications (2025). DOI: 10.1038/s41467-025-57659-z ...
The study found that RNA sequences that form hairpin structures began to adopt new, compact forms below 20 °C. Ritort added, “ All the RNA molecules studied share unexpected novel structures at ...
The crystal structure of a hairpin ribozyme–inhibitor complex demonstrates how an RNA that catalyses a transesterification can align the 2′-OH nucleophile and the 5′-oxo leaving group of the ...
No high-resolution data on the tertiary structure of the hairpin ribozyme are yet available 13.Previous evidence has shown that catalytic activity requires a sharp bend about the hinge of the ...
Micro RNA (miRNA, hsa-miR-133a) structure, computer model. (molekuul_be | Shutterstock). Short hairpin RNA (shRNA) synthesis. Short hairpin RNA (shRNA) are produced in the nucleus of transduced or ...
The study identified RNA helicases, specifically RH37-like helicases, as enzymes involved in unwinding hairpin structures near uAUGs during the immune response in Arabidopsis.
With a $50 million initial investment from Flagship, Terrana will use RNA from benign plant viruses as a chassis to carry ...
Their discovery of a novel mini hairpin structure in a nascent peptide that induces translation arrest sheds light on peptide-mediated regulatory mechanisms. Credit Dr. Yuhei Chadani from Okayama ...
A hairpin opens up the receptor "We have been able to crystallize the complex formed by the V protein and MDA5 for the first time, and have determined its three-dimensional structure in detail ...
A research team led by scientists from the Hong Kong University of Science and Technology (HKUST) has revealed how secondary structure RNA elements control the cleavage activity of the DICER ...
Back in 2006, Andrew Fire and Craig Mello won the Nobel Prize in Physiology or Medicine for their discovery of RNA interference in "silencing" genes. Today, nearly a decade later, the technology ...
RNA serves a wide variety of roles within a cell, carrying out catalytic, regulatory, structural and genetic transferal functions. A type of artificial RNA, called short hairpin RNA (shRNA ...