Computer simulations help materials scientists and biochemists study the motion of macromolecules, advancing the development ...

Metabolic syndrome—a constellation of conditions including insulin resistance, obesity, hypertension, and dyslipidemia—is a ...

This valuable study presents an analysis of evolutionary conservation in intrinsically disordered regions, identified as key drivers of phase separation, leveraging a protein language model. The ...

To address this, we developed a machine learning-based predictive model for HPD risk across cancer types, integrating clinical and molecular data. Methods: This study analyzed data from 1, 005 ...

Many chemists are excited about the capabilities they can bring to bear with new drug modalities. But the profusion of new types of molecules also raises a tough question for early-stage drug ...

Center for Soft Condensed Matter Physics and Interdisciplinary Research, School of Physical Science and Technology, Soochow University, Suzhou, Jiangsu 215006, China Beijing National Laboratory for ...

Faculty of Biochemistry and Molecular Medicine, University of Oulu, Aapistie 5 A, 90220 Oulu, Finland Biocenter Oulu, University of Oulu, Aapistie 5 A, 90220 Oulu, Finland ...

This manuscript describes the characterization of the conformational dynamics of two chemokine receptors at the single-molecule level using FRET ... To evaluate the appropriate level of model ...

A common mineral, α-alumina, found abundantly in Earth's crust, may have played a critical role in initiating the chemical reactions necessary for life to begin. This exciting discovery, detailed ...

DESeq2 was employed to model raw reads, using scale factors to account for variations in library depth. Gene dispersion was subsequently assessed using DESeq2, enhancing the precision of dispersion ...