Muscimol, a GABA-A (GABAA) receptor agonist, enhances GABA's inhibitory effect on neuronal activity by activating GABAA ...

Delandistrogene moxeparvovec (Elevidys; Sarepta Therapeutics) appeared to protect muscle from progressive damage in patients ...

Collectively, the data from in vitro and in vivo studies using FUS, TDP-43, and C9orf72 models demonstrate that hUPF1 holds significant potential for treating the majority of patients with ALS and ...

Line 467A shows expression limited to cells in the optic and olfactory ... neuronal subsets that did not include those critical for the behavior. Cells lacking GFP expressed FLP and successfully ...

The GFP expression presented a punctiform pattern in seminiferous ... tested in the context of infertility treatment before this study. When using the EEV vector, expression persisted for longer – up ...

This was evidenced by the ability of CUTS to detect modest levels of TDP-43 LOF, as shown by the dose-responsive increase in the expression of the reporter gene, GFP, under various ... were and ...

Upon DSB induction, proviral vector integration occurs at the targeted break site ... were sorted and grown to perform sgRNA infections and CFA under Taxol selection. X‐axis shows GFP expression ...

It is also possible to synthesize all potential off-targets with microarray and clone them into the vector to establish a library. The library is stably integrated into chromosome. Transfection of ...

In our study, cell lines from different species were used to evaluate Ad11 prototype (Ad11p) vector-based transgene expression and then determine the susceptibility of animal cells to Ad11p infection.

Evaluation by flow cytometry experiments of the basal (t = 0) and induced expression of GFP along time upon induction of the ... respect to the control strain transformed with the empty vector to ...

Here, we developed an atrial-specific gene transfer vector containing a shortened ANF promoter. AAV9 vectors containing a 653 bp segment of the mouse Nppa promoter 10 were used to drive expression of ...

Second, we sought to determine the threshold of endogenous protein expression that yields a sufficient level of GFP fluorescence for the detection ... were generated by lentiviral integration from the ...