Learn how cell-free protein synthesis helps researchers overcome the challenges of traditional membrane protein production ...

The amino acid sequence of a protein encodes its three-dimensional structure and determines its biological function. Although researchers can readily generate proteins with altered amino acid ...

Every protein in the body is encased in a water shell that directs protein structure, provides vital stability and steers ...

Two key protein structures in the body are being visualized for the first time, thanks in part to the latest technology — ...

By designing proteins de novo scientists can more efficiently create novel therapeutics tailored for specific biological functions.

Proteins control all vital processes in every organism, for example growth and metabolism. A basic principle of protein ...

Functional protein design, ... deep learning models face challenges in modeling complex molecular–protein interactions and capturing sequence-structure dependencies.

De novo protein design. In 2024, David Baker won the Nobel Prize in Chemistry for computational protein design and the prize was shared with Demis Hassabis, and John Jumper for protein structure ...

Every protein in the body is encased in a water shell that directs protein structure, provides vital stability and steers function. Because of this, water molecules represent a powerful but largely ...

Predicting proteins’ structure from their amino acid sequences had stumped researchers since the 1970s. But in 2020, Hassabis and Jumper developed an artificial intelligence model called AlphaFold2.