Increased dietary folic acid intake may lead to adverse health effects, including inflammation and neurotoxicity, ...

According to the National Institutes of Health, about seven in 10 autistic children have folate receptor autoantibodies, a ...

Ramaekers and Quadros found that autoantibodies against the folate receptor alpha (FR⍺), which transports folic acid from the blood into the brain and the placenta, might cause abnormal fetal ...

Role of Folate Receptor Alpha Testing Mirvetuximab soravtansine, an antibody-drug conjugate targeting FRα, represents the newest approved therapy in ovarian cancer. Testing considerations include ...

For example, when we inactivate (knock out) the folate receptor (Forl1) gene-its protein product which is a receptor molecule that brings vitamin B9 (folic acid) into cells is eliminated, and the ...

A retrospective study showed that either folate receptor alpha or B7-H4 was expressed in more than 80% of endometrial cancers ...

Rinatabart sesutecan (Rina-S) is an antibody-drug conjugate that targets folate receptor-alpha (FRα) and delivers a TOP1 inhibitor directly to cancer cells, according to a press release, which went on ...

Bio-Thera Solutions Inc. (688177:SH), a commercial-stage biopharmaceutical company developing a pipeline of innovative ...

Strong rationale for use of small molecule drug conjugate in cancers that overexpress the folate receptor, such as ovarian cancer, triple negative breast cancer and non-small cell lung cancer. Team ...