Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly ...

A team of scientists has answered a long-standing question in cell biology, uncovering how the cell's main energy currency, ATP, is transported into the endoplasmic reticulum (ER). Disrupted energy ...

Researchers have answered a a long-standing question in cell biology, uncovering how the cell’s main energy currency, ATP, is ...

Pulmonary fibrosis is a lung disease with limited therapeutic options and the development of new therapeutics is a clinical ...

Understanding how the energy-carrying molecule in cells does its job may have major implications for combating cancer and type 2 diabetes, among other diseases.

A team of scientists has answered a long-standing question in cell biology, uncovering how the cell's main energy currency, ...

A team of scientists has answered a long-standing question in cell biology, uncovering how the cell's main energy currency, ATP, is transported into ...

Junctions between the endoplasmic reticulum (ER) and the outer membrane of the nuclear envelope (NE) physically connect both organelles. These ER–NE junctions are essential for supplying the NE with ...

Cln-619 (anti-MICA/B antibody) alone and in combination with pembrolizumab (P) for advanced solid tumors: Updated results of a Ph1 study. This is an ASCO Meeting Abstract from the 2024 ASCO Annual ...

have shown how the recycling of ribosomes at the so-called endoplasmic reticulum (ER) functions. In the process, they discovered the role of an enzyme, a special E3 ligase that joins a small ...

The endoplasmic reticulum (ER) is an organelle with distinct structural domains associated with specific functions. The ER dynamically changes its mass, components, and shape in response to metabolic, ...