Unlocking the Potential of siRNA for Drug Development siRNA therapeutics represent a paradigm shift in targeted drug development by enabling precise gene silencing of disease-causing genes.

Mallinckrodt and Endo, pharmaceutical companies that have each encountered business struggles, announced Thursday a $6.7 billion merger that they contend will result in a combined entity with the ...

Net Leverage of Approximately 2.3x Expected at Close Mallinckrodt and Endo plan to combine their generic pharmaceuticals businesses and Endo's sterile injectables business after the close of the ...

Mallinckrodt plc and Endo, Inc. today announced that they have entered into a definitive agreement to combine in a stock and cash transaction to create a global, scaled, diversified ...

Two start-ups have launched to develop next-generation drugs using small interfering RNA (siRNA) to silence genes. The first, Judo Bio, is a spin-off of the venture capital firm Atlas Venture.

NMR-based analysis of impact of siRNA mixing conditions on internal structure of siRNA-loaded LNP. Journal of Controlled Release , 2024; 373: 738 DOI: 10.1016/j.jconrel.2024.07.055 Cite This Page : ...

Nomura believes the research has potential applications as siRNA drugs for diseases such as hereditary transthyretin amyloidosis, acute hepatic porphyria, primary hyperoxaluria type 1, primary ...

This distressing symptom is commonly known as endo belly. Endometriosis is a disorder in which tissue similar to the tissue that lines the uterus grows outside the uterus in places where it doesn ...

Feb. 29 (UPI) --Opioid manufacturer Endo Health Solutions reached an agreement with the U.S. government Thursday to resolve criminal and civil cases stemming from its contribution to the opioid ...

Editor's note: This story was updated to note that Endo's criminal and civil opioid settlement payments will be satisfied by the bankruptcy resolution, according to an Endo spokesperson.

Lab data in cells has shown that siRNA has the potential to treat COVID-19 infection better than existing antivirals, according to new research from UNSW's Kirby and RNA Institutes, published ...

Aug 9 (Reuters) - Endo International (ENDPQ.PK), opens new tab has sued Zydus Pharmaceuticals (ZYDU.NS), opens new tab in Delaware federal court, claiming Zydus violated its patent rights with a ...