DNA detection at baseline was associated with worse recurrence-free, overall survival in BRAFV600-mutant stage III melanoma.

We furthermore demonstrate that AM reprogramming at both the transcriptional and metabolic levels exacerbate lung injury following bacterial (LPS) or viral (polyI:C) challenges via a neutrophil/IFN-γ ...

Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-Sen University, Guangzhou, Guangdong 510055, China Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-Sen University, ...

C57BL/6 mice deficient in interleukin12 or gamma interferon showed faster acute vascular rejection than did wild-type mice. Furthermore, mice defective in B-cell development showed no acute ...

Tumour cell-intrinsic peroxisome proliferator-activated receptor-gamma (PPARγ) upregulation orchestrates an MDSC-enriched and T cell-dysfunctional TME through vascular endothelial growth factor-A ...

From the Department of Cardiology and Angiology I, University Heart Center Freiburg, Germany (D.W.) Faculty of Medicine, University of Freiburg, Germany (D.W.) K. Ley has received research funding for ...

ELISA showed CLP surgery significantly elevated serum levels of these cytokines. Anti-CD47 antibody or E2609 treatment significantly reduced their levels. CD47-KO mice exhibited similar reductions, ...

Integrated Multi-User Laboratory in Applied Biotechnology, Institute of Biological Sciences, University of Pernambuco, Santo Amaro, Recife, Pernambuco 50100-130, Brazil Biotechnology and Parasitology ...

Supernatants from DC/T cell cultures were collected. Cytokine secretion levels were analyzed via ELISA for mouse interferon gamma (IFN-γ) secretion, following manufacturer instructions (BD). 96-well ...

THP-1 cells could differentiate into resting macrophages with phorbol-12-myristate-13-acetate (PMA) and then polarize into M1 macrophages following treatment with lipopolysaccharide (LPS) and ...