E1s and E2s first work generically across the cell to activate and prepare ubiquitin for attachment. E3 ligases then ensure that the tag is added to the right protein; as such, hundreds of specific ...

Researchers from the National University of Singapore (NUS) have pioneered a new catalytic transformation that converts ...

Precise calculations of binding free energy are pivotal in reducing the high costs and inefficiencies of drug discovery. A recent study presents PairMap, an innovative computational tool that ...

Researchers have developed a powerful computational tool, named iDOMO, to improve the prediction of drug synergy and accelerate the development of combination therapies for complex diseases. The study ...

Researchers at the Icahn School of Medicine at Mount Sinai have developed a powerful computational tool, named iDOMO, to improve the prediction of drug synergy and accelerate the development of ...

Earlier this month, the Trump administration directed the National Institutes of Health (NIH) to impose limits on specific ...

Shivaram has a prior criminal record, having been involved in drug-related and other offences, including cases registered under the NDPS Act at the Excise Police Station, Shamshabad, and another ...

Conduit and Sarborg complete all milestones of Phase I of their AI-driven drug development collaboration, and commence transitioning to Phase II, ...

Drug addiction is a condition in which there is uncontrolled use of a substance with a harmful outcome. Drugs overstimulate the brain’s reward circuit, producing pleasure or euphoria. With repeated ...

Earnings declined around 23% year over year due to increased IPR&D expenses incurred during ... The upside can be attributed to label expansions of the drug to include new patient populations ...

Meerut/Bareilly: Ram Sevak, the former Faridpur inspector, who was accused of accepting bribes for releasing drug traffickers ... leading to the discovery of over Rs 9 lakh.

Drug discovery and development together are the complete process of identifying a new drug and bringing it to market. Discovery may involve screening of chemical libraries, identification of the ...