"While most organs are thought to be shaped by static, brick-like cells, our study highlights the powerful role of dynamic, migrating cells—and how they work together to sculpt living tissue ...

In prostate and breast cancer cells, removing CD36 blocked the cancer-fighting power of these drugs. This wasn’t just true for PROTACs but for other large drugs too, like doxorubicin and navitoclax.

Abnormal amino acid metabolism supports cancer cell proliferation, invasion, and immune evasion in hepatocellular carcinoma (HCC). Previous research exploring amino acid metabolism in HCC has ...

Therefore, the development of protein thiol target fluorescent probe is highly desirable. In the present work, a biotinylated coumarin fluorescence “off–on” probe SQ for selectively detecting protein ...

With more than 4,000 cell, gene, and RNA therapies in development, Cannon said, that is “a very big iceberg.” Charles Gersbach, PhD, a co-founder of Tune Therapeutics, discussed the potential ...

Statistical analysis An analysis of variance was used to compare the dependent variables (AEW, LP, DFC, FC) with different levels of methionine+cystine in the quails’ diet, after which pairwise ...

Landmark trials using stem cells to treat Parkinson’s disease in the USA and Japan mark a turning point for cell therapy in neurodegeneration. Similar approaches to Alzheimer’s disease and ...