The study, published in Cell, reveals how cyclic dinucleotides (CDNs), synthesized during the activation of the cyclic oligonucleotide-based anti-phage signaling system (CBASS) immune mechanism ...

To avoid ambiguity, adjuvants (e.g., TLR agonists, cyclic dinucleotides) is restricted to the components enhancing immune responses although certain adjuvants (e.g., particulate carriers like alum or ...

In light of this, in this paper, we propose a two-dimensional (2D) cyclic chaotic system (2D-CCS) and design a novel chaos-based secure communication scheme called noise-reduced orthogonal frequency ...

Intriguingly, the two cyclic peptides not only tolerate Gβγ while inhibiting Gα, but even actively promote the PPI between the inhibited Gα and Gβγ through direct engagement of R96/D118:Gβ. Because ...

Department of Chemistry, Northwestern University, Evanston, Illinois 60208, United States International Institute for Nanotechnology, Northwestern University, Evanston, Illinois 60208, United States ...

The objective of this paper is to construct several infinite families of MDS, near MDS and almost MDS codes from some special cyclic subgroups of ${\mathbb {F}}_{q^{2}}^{*}$ . To this end, the ...

The ability to reprogram mature, differentiated cells into induced pluripotent stem cells (iPSCs) using exogenous pluripotency factors opened up unprecedented opportunities for their application in ...

Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria 3052, Australia Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia Sir Peter MacCallum ...