In conclusion, in addition to cAMP-related mechanisms, the renal vasodilator effects of AM ... Bar graphs show effects of adrenomedullin (AM) on urinary excretion of sodium (UNaV), cyclic AMP (UcAMPV) ...

Edited by Lily Jan, Howard Hughes Medical Institute–University of California San Francisco, San Francisco, CA; received August 17, 2024; accepted March 3, 2025 ...

Expanding on these findings, the researchers discovered that this Cer-based intercellular UPR signaling mechanism has broader applicability, offering a new theoretical framework for understanding ...

Melissa Quinn is a politics reporter for CBSNews.com. She has written for outlets including the Washington Examiner, Daily Signal and Alexandria Times. Melissa covers U.S. politics, with a focus ...

Chen’s discovery of cGAS, short for cyclic guanosine monophosphate-adenosine monophosphate synthase, in 2013 was a key part of filling in the gaps of knowledge in innate immune signaling ... was a ...

Several nucleic acid sensors or families have been identified, such as RIG-I-like receptors (RLRs), Toll-like receptors (TLRs), cyclic GMP-AMP synthase ... provide more accurate insights into the ...

In this review, we present an updated overview on the influence of cAMP-mediated immunoregulatory mechanisms acting through localized cAMP signaling and the therapeutical increasing prospects of AKAPs ...