In a mouse model of chronic stress, 20 days of corticosterone injections reduced dendritic spine density and induced behavioral changes suggesting the depression of cognitive inflexibility.

A core point in her work is that people who display cognitive inflexibility in tests mapping their ability to adjust to change also adhere to more rigid, radical and extreme ideologies.

Negative symptoms and cognitive deficits play a major role in psychosis and significantly influence the functional outcomes of patients, particularly those with a first episode of psychosis (FEP).

His research work centers on determining the circuit mechanisms underlying stress-induced cognitive inflexibility, a transdiagnostic dysfunction observed in various psychopathologies, including ...

Cognitive functioning affects how people think and their ability to remember things. Impairment in this area of brain health may cause a decline in how someone responds to their environment ...

"Cognitive inflexibility is a hallmark of the condition often arising before symptoms of anorexia nervosa are obvious, and persisting after weight recovery – making this symptom a primary target for ...

These studies argue that the conservative emphasis on maintaining the status quo could reflect cognitive inflexibility, making such ideologies more attractive to those who struggle with ...

Hur’s report, in which he declined to prosecute President Biden for his handling of classified documents, also included a much-debated assessment of Mr. Biden’s cognitive abilities.

Cognitive fatigue is the deterioration in the ability to think effectively and maintain focus. Just like physical fatigue, prolonged mental activity can cause tiredness that affects the mind.