To enhance CAR T therapies, scientists are actively studying TCR signaling and T-cell exhaustion mechanisms to improve CAR T ...

The discovery of the Kozak consensus sequence revealed that certain nucleotide contexts around the initiation codon can significantly enhance the efficiency of initiation codon recognition. Since then ...

Have you ever wondered how horses became such powerful and enduring runners? Scientists at Medicine believe they’ve found the ...

A genetic mutation and evolutionary trick fuels horses' exceptional athleticism, findings that may advance scientific ...

Researchers have pinpointed a genetic mutation and evolutionary process that appears to have optimized horses’ speed and ...

Horses have a rare genetic adaptation that helps improve athleticism. This evolutionary mechanism could improve human ...

The Creative Biogene division IntegrateRNA launched a novel platform that enables post-translational protein modification through the use of non-canonical amino acids and engineered transfer RNA. The ...

While mRNA vaccines represent a transformative platform for infectious disease control, their efficacy in antigen-presenting cells (APCs) remains vulnerable to endogenous regulatory networks, ...

In the full study, conducted in collaboration with the Castiglione Lab at Vanderbilt University and partially funded by the ...

The study is published in the journal Nature Communications. Normally, on subsequently encountering a stop codon in the transcript, peptide release factors (RF) trigger the dissociation of the ...