Within chromatin, structures called packing domains form when chromatin fibers fold together. These chromatin packing domains are critical for regulating gene expression, DNA replication and ...

Kanazawa University and colleagues have achieved a breakthrough in understanding sperm DNA packaging. Using high-speed atomic ...

However, the researchers discovered that chromatin, the packaging of DNA within the cell nucleus, continues to open even when the key protein for gene activation, CBP, is absent. According to the team ...

A study by scientists at the Herbert Irving Comprehensive Cancer Center (HICCC) introduces a more cost-effective, scalable ...

The chip that is inserted into the 10X Genomics software, allowing researchers to analyze DNA and RNA simultaneously.

which is a major driver of chromatin packaging. Epigenetics does not alter the sequence of DNA, but instead impacts gene expression by changing the compactness of chromatin. According to the U.S.

In a major breakthrough for diabetes treatment, scientists have found a new way to regenerate insulin-producing cells. This ...

However, the DNA is contained within the nucleus, which is only around 6 μm in diameter, due to compaction by packaging it as chromatin. Chromatin consists of nucleosomes, the basic structural unit of ...