Zhang et al. present important findings that reveal a new role for TET2 in controlling glucose production in the liver, showing that both fasting and a high-fat diet increase TET2 levels, while its ...

Epigenetic regulation orchestrated by changes in chromatin openness modulates behavioral plasticity by controlling gene expression. However, the gene regulation mechanisms by which chromatin openness ...

Methods: In this study, we integrated biochemical assays with a panel of cellular analyses ... through integrated network pharmacology approaches. Chromatin immunoprecipitation quantitative PCR ...