Two strands result. One, dubbed the "sense" strand, carries genetic information. The other, the antisense strand, says nothing. In theory, scientists can use antisense molecules to block the ...

The sensitive system, which can detect fewer than 10 copies of a target, can be used with any real-time thermocycler and works via a simple amplification and cleavage reaction.Appended to the ...

The siRNA antisense strand guides RISC to the target mRNA, resulting in endonucleolytic cleavage. Important features in designing siRNA are specific target recognition and minimization of off ...

One significant class of such ncRNA is natural antisense transcripts (NATs ... including plant genome encode large amount of NATs transcribed either from opposite strand of genes (cis-NAT) or from ...

The outcome of these developments is expected to impact the entire field of antisense technology. Although other companies, including Novopharm Biotech (Winnipeg, Manitoba, Canada), Hybridon ...